Search on:
ALPHA-MSH
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
alpha-MSH
Descriptor
Spanish
:
alfa-MSH
Descriptor
Portuguese
:
alfa-MSH
Synonyms
English
:
MSH, alpha
alpha-Melanocyte-Stimulating Hormone
Tree Number:
D06.472.699.327.935.179
D06.472.699.327.935.531.750.050
D06.472.699.631.525.600.179
D06.472.699.631.525.600.531.750.050
D12.644.400.400.935.179
D12.644.400.400.935.531.750.050
D12.644.400.460.050
D12.644.548.365.935.179
D12.644.548.365.935.531.750.050
D12.644.548.691.525.690.179
D12.644.548.691.525.690.531.750.050
D12.776.641.650.405.935.179
D12.776.641.650.405.935.531.750.050
D12.776.641.650.460.050
Definition
English
:
A 13-amino acid peptide derived from proteolytic cleavage of
ADRENOCORTICOTROPIC HORMONE
, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form
alpha-MSH
in the secretory granules.
Alpha-MSH
stimulates the synthesis and distribution of MELANIN in
MELANOCYTES
in
mammals
and
MELANOPHORES
in lower
vertebrates.
Pharmacological Action:
Hormones
History Note
English
:
1988 (1981)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
22828
Unique Identifier:
D000521
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS