Search on: DYNORPHINS 
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Descriptor English:   Dynorphins 
Descriptor Spanish:   Dinorfinas 
Descriptor Portuguese:   Dinorfinas 
Tree Number:   D12.644.400.575.180
D12.644.468.180
D12.776.641.650.575.180
Definition English:   A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters. 
Pharmacological Action:   Neurotransmitter Agents
 
See Related English:   Receptors, Opioid, kappa
 
History Note English:   95; was DYNORPHIN 1985-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   22432 
Unique Identifier:   D004399 

Occurrence in VHL:
 

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