Pesquisa sobre:
ANGIOPOIETIN-2
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Angiopoietin-2
Descritor
Espanhol
:
Angiopoyetina 2
Descritor
Português
:
Angiopoietina-2
Categoria:
D12.644.276.100.100.200
D12.776.467.100.100.200
D23.529.100.100.200
Definição
Inglês
:
An angiopoietin that is closely related to
ANGIOPOIETIN-1
. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of
ANGIOPOIETIN-1
. However its antagonistic effect may be limited to cell receptors that occur within the vasculature.
Angiopoietin-2
may therefore play a
role
in
down-regulation
of
BLOOD
VESSEL branching and sprouting.
Nota Histórica
Inglês
:
2004; use ANGIOPOIETIN-2 (NM) 1997-2003
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Número do Registro:
38239
Identificador Único:
D042702
Ocorrência na BVS
:
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