Search on:
QUININE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Quinine
Descriptor
Spanish
:
Quinina
Descriptor
Portuguese
:
Quinina
Tree Number:
D03.132.206.719
D03.438.810.762
D03.605.687.762
Definition
English
:
An alkaloid derived from the bark of the
cinchona
tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the
cinchona
that have been used for that purpose since before 1633.
Quinine
is also a mild antipyretic and analgesic and has been used in
common cold
preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of
babesiosis
.
Quinine
is also useful in some muscular disorders, especially nocturnal
leg
cramps and
myotonia congenita
, because of its direct effects on muscle membrane and
sodium channels
. The mechanisms of its antimalarial effects are not well understood.
Indexing Annotation
English
:
/biosyn permitted if by plant
Pharmacological Action:
Analgesics, Non-Narcotic
Antimalarials
Muscle Relaxants, Central
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
12240
Unique Identifier:
D011803
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS