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OXOCHOLESTEROLS
Descriptors Found:
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DeCS
Descriptor
English
:
Ketocholesterols
Descriptor
Spanish
:
Cetocolesteroles
Descriptor
Portuguese
:
Cetocolesteróis
Synonyms
English
:
Oxocholesterols
Tree Number:
D04.808.247.222.265.450
D04.808.247.222.284.600
D04.808.247.808.197.600
D10.570.938.208.650
Definition
English
:
Cholesterol
substituted in any position by a keto moiety. The 7-keto isomer inhibits 3-hydroxy-3-methylglutaryl-CoA reductase activity and inhibits
cholesterol
uptake in the coronary
arteries
and
aorta
in vitro.
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
91(80); was see under CHOLESTEROL 1980-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7818
Unique Identifier:
D007653
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS