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OSTEOPONTIN
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DeCS
Descriptor
English
:
Osteopontin
Descriptor
Spanish
:
Osteopontina
Descriptor
Portuguese
:
Osteopontina
Tree Number:
D12.644.276.374.625
D12.776.395.700.837
D12.776.467.374.625
D12.776.860.300.762
D23.529.374.625
Definition
English
:
A negatively-charged
extracellular matrix
protein that plays a
role
in the regulation of BONE
metabolism
and a variety of other biological functions. Cell signaling by
osteopontin
may occur through a
cell adhesion
sequence that recognizes INTEGRIN ALPHA-V BETA-3.
History Note
English
:
2007(1987)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52284
Unique Identifier:
D053495
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS