Expresión de búsqueda: ANGIOPOIETIN-2 
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Descriptor Inglés:   Angiopoietin-2 
Descriptor Español:   Angiopoyetina 2 
Descriptor Portugués:   Angiopoietina-2 
Categoría:   D12.644.276.100.100.200
D12.776.467.100.100.200
D23.529.100.100.200
Definición Inglés:   An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting. 
Nota Histórica Inglés:   2004; use ANGIOPOIETIN-2 (NM) 1997-2003 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número del Registro:   38239 
Identificador Único:   D042702 

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