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CHIMERIN 1
Descriptors Found:
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DeCS
Descriptor
English
:
Chimerin 1
Descriptor
Spanish
:
Quimerina 1
Descriptor
Portuguese
:
Quimerina 1
Synonyms
English
:
alpha-Chimerin
alpha-1 Chimerin
alpha-2 Chimerin
arhGAP2 Protein
n-Chimerin
rhoGAP2 Protein
Tree Number:
D12.644.360.325.150.100.200
D12.776.402.150.100.200
D12.776.476.325.150.100.200
D12.776.641.124.200
Definition
English
:
A GTPase activating protein that is specific for
RAC GTP-BINDING PROTEINS
. It is expressed primarily in the
brain
and may be involved in
signal transduction
. The alternatively spliced form of
CHIMERIN 1
(alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the
brain
and testes.
History Note
English
:
2000; use CHIMERIN 1 (NM) 1990-1999; for ALPHA1-CHIMAERIN use GTPASE-ACTIVATING PROTEINS (NM) 1996-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34484
Unique Identifier:
D020848
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS