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LEVODOPA
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DeCS
Descriptor
English
:
Levodopa
Descriptor
Spanish
:
Levodopa
Descriptor
Portuguese
:
Levodopa
Synonyms
English
:
L-Dopa
Tree Number:
D02.092.311.200.480
D12.125.072.050.685.400.500
D12.125.072.050.875.130.500
Definition
English
:
The naturally occurring form of
DIHYDROXYPHENYLALANINE
and the immediate precursor of
DOPAMINE
. Unlike
dopamine
itself, it can be taken orally and crosses the
blood-brain barrier
. It is rapidly taken up by
dopaminergic neurons
and converted to
DOPAMINE
. It is used for the treatment of
PARKINSONIAN DISORDERS
and is usually given with agents that inhibit its conversion to
dopamine
outside of the
central nervous system.
Pharmacological Action:
Antiparkinson Agents
Dopamine Agents
See Related
English
:
Dopamine
History Note
English
:
75; was see DOPA 1972-74
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24230
Unique Identifier:
D007980
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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