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P300-CBP TRANSCRIPTION FACTORS
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DeCS
Descriptor
English
:
p300-CBP Transcription Factors
Descriptor
Spanish
:
Factores de Transcripción p300-CBP
Descriptor
Portuguese
:
Fatores de Transcrição de p300-CBP
Tree Number:
D08.811.913.050.134.440
D12.776.930.622
Definition
English
:
A
family
of
histone acetyltransferases
that is structurally-related to
CREB-BINDING PROTEIN
and to
E1A-ASSOCIATED P300 PROTEIN
. They function as transcriptional coactivators by bridging between DNA-binding
TRANSCRIPTION FACTORS
and the basal transcription
machinery
. They also modify
transcription factors
and
CHROMATIN
through
ACETYLATION.
History Note
English
:
2006(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50671
Unique Identifier:
D050880
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS