Search on: GAMMA-GLUTAMYLCYCLOTRANSFERASE 
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Descriptor English:   gamma-Glutamylcyclotransferase 
Descriptor Spanish:   gamma-Glutamilciclotransferasa 
Descriptor Portuguese:   gama-Glutamilciclotransferase 
Tree Number:   D08.811.913.050.200.400
Definition English:   An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines. EC 2.3.2.4. 
Indexing Annotation English:   do not confuse with GAMMA-GLUTAMYLTRANSFERASE
History Note English:   91(75); was see under ACYLTRANSFERASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   5861 
Unique Identifier:   D005722 

Occurrence in VHL:
 

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