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THYMIDYLATE SYNTHASE
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DeCS
Descriptor
English
:
Thymidylate Synthase
Descriptor
Spanish
:
Timidilato Sintasa
Descriptor
Portuguese
:
Timidilato Sintase
Tree Number:
D08.811.913.555.500.862
Definition
English
:
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of
thymidine
triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
History Note
English
:
98; see METHYLTRANSFERASES 1975-85
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
14327
Unique Identifier:
D013940
Occurrence in VHL
:
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DeCS
CID-10
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