Search on: THIOCTIC ACID 
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Descriptor English:   Thioctic Acid 
Descriptor Spanish:   Ácido Tióctico 
Descriptor Portuguese:   Ácido Tióctico 
Synonyms English:   Lipoic Acid  
Tree Number:   D02.241.803
D02.886.778.827
D08.211.906
D10.251.941
Definition English:   An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS. 
Pharmacological Action:   Antioxidants
Vitamin B Complex
 
History Note English:   91; was LIPOIC ACID 1963-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   29256 
Unique Identifier:   D008063 

Occurrence in VHL:
 

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