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SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS
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DeCS
Descriptor
English
:
Suppressor of Cytokine Signaling Proteins
Descriptor
Spanish
:
Supresor de Proteínas Señalizadoras de Citocinas
Descriptor
Portuguese
:
Proteínas Supressoras da Sinalização de Citocina
Tree Number:
D12.644.360.024.374
D12.776.157.057.249
D12.776.476.024.437
Definition
English
:
A
family
of structurally related
proteins
that are induced by
CYTOKINES
and negatively regulate cytokine-mediated
SIGNAL TRANSDUCTION
PATHWAYS. SOCS
proteins
contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50800
Unique Identifier:
D050826
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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