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SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS
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DeCS
Descriptor
English
:
Sodium Potassium Chloride Symporter Inhibitors
Descriptor
Spanish
:
Inhibidores del Simportador de Cloruro Sódico y Cloruro Potásico
Descriptor
Portuguese
:
Inibidores de Simportadores de Cloreto de Sódio e Potássio
Tree Number:
D27.505.519.562.906
D27.505.696.560.500.931
Definition
English
:
Agents that inhibit
SODIUM-POTASSIUM-CHLORIDE SYMPORTERS
which are concentrated in the thick ascending limb at the junction of the
LOOP OF HENLE
and
KIDNEY TUBULES
, DISTAL. They act as
DIURETICS
. Excess use is associated with
HYPOKALEMIA
and
HYPERGLYCEMIA.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
51201
Unique Identifier:
D049994
Occurrence in VHL
:
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