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DeCS
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Descriptor English:
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Receptor, Serotonin, 5-HT1D
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Descriptor Spanish:
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Receptor de Serotonina 5-HT1D
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Descriptor Portuguese:
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Receptor 5-HT1D de Serotonina
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Synonyms English:
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Serotonin 1D Receptor
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Tree Number:
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D12.776.543.750.070.800.100.200
D12.776.543.750.100.800.100.200
D12.776.543.750.720.300.800.100.200
D12.776.543.750.720.670.100.750
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Definition English:
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A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect. |
Entry Combination - descr/qualif English:
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Receptor, Serotonin, 5-HT1D/agonists use Serotonin 5-HT1 Receptor Agonists Receptor, Serotonin, 5-HT1D/antagonists & inhibitors use Serotonin 5-HT1 Receptor Antagonists
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History Note English:
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2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
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Allowable Qualifiers English:
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Record Number:
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38305
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Unique Identifier:
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D044346
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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