1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Retinoblastoma Protein
|
Descriptor Spanish:
|
|
Proteína de Retinoblastoma
|
Descriptor Portuguese:
|
|
Proteína do Retinoblastoma
|
Synonyms English:
|
|
p105-Rb Protein
Rb Protein
Retinoblastoma Nuclear Phosphoprotein p105-Rb
|
Tree Number:
|
|
D12.776.260.704
D12.776.624.776.745
D12.776.660.807
D12.776.744.770
|
Definition English:
|
|
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein. |
Indexing Annotation English:
|
|
/biosyn /drug eff /physiol /ultrastruct permitted
|
History Note English:
|
|
91
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
29109
|
Unique Identifier:
|
|
D016160
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|