Search on:
RABBIT AORTA CONTRACTING SUBSTANCE
Descriptors Found:
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DeCS
Descriptor
English
:
Thromboxane A2
Descriptor
Spanish
:
Tromboxano A2
Descriptor
Portuguese
:
Tromboxano A2
Synonyms
English
:
Rabbit Aorta Contracting Substance
Tree Number:
D10.251.355.255.100.825.800
D23.469.050.175.800.800
Definition
English
:
An unstable intermediate between the
prostaglandin endoperoxides
and
thromboxane B2
. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of
platelet aggregation
and causes
vasoconstriction
. It is the principal component of rabbit
aorta
contracting substance (RCS).
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
86(78); was see under THROMBOXANES 1978-85
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14314
Unique Identifier:
D013928
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS