Search on: NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE 
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Descriptor English:   Nicotinamide-Nucleotide Adenylyltransferase 
Descriptor Spanish:   Nicotinamida-Nucleótido Adenililtransferasa 
Descriptor Portuguese:   Nicotinamida-Nucleotídeo Adenililtransferase 
Synonyms English:   NAD Pyrophosphorylase
Nicotinamide Mononucleotide Adenylyltransferase
NMN Adenylyltransferase  
Tree Number:   D08.811.913.696.445.600
Definition English:   An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. EC 2.7.7.1. 
Indexing Annotation English:   DF: note short X ref
History Note English:   98(79) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   9799 
Unique Identifier:   D009612 

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