Search on: NADPH OXIDASE 
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Descriptor English:   NADPH Oxidase 
Descriptor Spanish:   NADPH Oxidasa 
Descriptor Portuguese:   NADPH Oxidase 
Tree Number:   D08.811.682.608.575
D12.776.331.894
Definition English:   A flavoprotein enzyme that catalyzes the univalent reduction of OXYGEN using NADPH as an electron donor to create SUPEROXIDE ANION. The enzyme is dependent on a variety of CYTOCHROMES. Defects in the production of superoxide ions by enzymes such as NADPH oxidase result in GRANULOMATOUS DISEASE, CHRONIC. 
See Related English:   Granulomatous Disease, Chronic
 
History Note English:   1997 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   33021 
Unique Identifier:   D019255 

Occurrence in VHL: 		 

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