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MELANOCYTE-STIMULATING HORMONES
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DeCS
Descriptor
English
:
Melanocyte-Stimulating Hormones
Descriptor
Spanish
:
Hormonas Estimuladoras de los Melanocitos
Descriptor
Portuguese
:
Hormônios Estimuladores de Melanócitos
Synonyms
English
:
MSH
Melanotropin
Tree Number:
D06.472.699.327.935.531.750
D06.472.699.631.525.600.531.750
D12.644.400.400.935.531.750
D12.644.400.460
D12.644.548.365.935.531.750
D12.644.548.691.525.690.531.750
D12.776.641.650.405.935.531.750
D12.776.641.650.460
Definition
English
:
Peptides
with the ability to stimulate pigmented
cells
MELANOCYTES
in
mammals
and
MELANOPHORES
in lower
vertebrates
. By stimulating the synthesis and distribution of MELANIN in these pigmented
cells
, they increase coloration of
skin
and other tissue. MSHs, derived from
pro-opiomelanocortin
(POMC), are produced by
MELANOTROPHS
in the INTERMEDIATE LOBE OF PITUITARY;
CORTICOTROPHS
in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic
neurons
in the
ARCUATE NUCLEUS.
Pharmacological Action:
Hormones
History Note
English
:
2006(1963)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23523
Unique Identifier:
D009074
Occurrence in VHL
:
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