Search on: HEPATOCYTE NUCLEAR FACTORS 
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Descriptor English:   Hepatocyte Nuclear Factors 
Descriptor Spanish:   Factores Nucleares del Hepatocito 
Descriptor Portuguese:   Fatores Nucleares de Hepatócito 
Tree Number:   D12.776.260.262
D12.776.660.352
D12.776.930.323
Definition English:   Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50995 
Unique Identifier:   D051536 

Occurrence in VHL: 		 

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