Search on: HEPATOCYTE NUCLEAR FACTOR 1 
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Descriptor English:   Hepatocyte Nuclear Factor 1 
Descriptor Spanish:   Factor Nuclear 1 del Hepatocito 
Descriptor Portuguese:   Fator 1 Nuclear de Hepatócito 
Tree Number:   D12.776.260.262.500
D12.776.660.352.500
D12.776.930.323.500
Definition English:   A transcription factor that regulates the expression of a large set of hepatic proteins including SERUM ALBUMIN; beta-fibrinogen; and ALPHA 1-ANTITRYPSIN. It is composed of hetero- or homo-dimers of HEPATOCYTE NUCLEAR FACTOR 1-ALPHA and HEPATOCYTE NUCLEAR FACTOR 1-BETA. 
History Note English:   2006(1989) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50996 
Unique Identifier:   D051537 

Occurrence in VHL: 		 

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