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HEPARIN COFACTOR II
Descriptors Found:
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DeCS
Descriptor
English
:
Heparin Cofactor II
Descriptor
Spanish
:
Cofactor II de Heparina
Descriptor
Portuguese
:
Cofator II da Heparina
Tree Number:
D12.644.822.750.060.750
D12.644.861.060.750
D12.776.124.790.106.450
D12.776.377.715.085.450
D12.776.645.750.060.750
D12.776.872.060.750
Definition
English
:
A sulfated
plasma
protein with a MW of approximately 66kDa that resembles
ANTITHROMBIN III
. The protein is an inhibitor of
thrombin
in
plasma
and is activated by
dermatan sulfate
or
heparin
. It is a member of the serpin superfamily.
Pharmacological Action:
Antithrombins
Serine Proteinase Inhibitors
History Note
English
:
90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
24709
Unique Identifier:
D015844
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS