Search on: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 10 
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Descriptor English:   GRB10 Adaptor Protein 
Descriptor Spanish:   Proteína Adaptadora GRB10 
Descriptor Portuguese:   Proteína Adaptadora GRB10 
Synonyms English:   Growth Factor Receptor-Bound Protein 10  
Tree Number:   D12.644.360.024.300
D12.776.157.057.029
D12.776.476.024.380
Definition English:   A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSULIN-LIKE GROWTH FACTOR RECEPTOR. It contains a C-terminal SH2 DOMAIN and mediates various SIGNAL TRANSDUCTION pathways. 
History Note English:   2006(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50768 
Unique Identifier:   D051383 

Occurrence in VHL: 		 

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