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GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR
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DeCS
Descriptor
English
:
Glial Cell Line-Derived Neurotrophic Factor
Descriptor
Spanish
:
Factor Neurotrófico Derivado de la Línea Celular Glial
Descriptor
Portuguese
:
Fator Neurotrófico Derivado de Linhagem de Célula Glial
Tree Number:
D12.644.276.860.381.500
D12.776.467.860.381.500
D12.776.641.600.381.500
D23.529.850.381.500
Definition
English
:
The founding member of the
glial cell line-derived neurotrophic factor
family
. It was originally characterized as a
NERVE GROWTH FACTOR
promoting the
survival
of MIDBRAIN
dopaminergic NEURONS
, and it has been studied as a potential treatment for
PARKINSON DISEASE.
Indexing Annotation
English
:
GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS
is also available
History Note
English
:
2006(1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
51102
Unique Identifier:
D051100
Occurrence in VHL
:
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