Search on: FANCONI ANEMIA COMPLEMENTATION GROUP L PROTEIN 
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Descriptor English:   Fanconi Anemia Complementation Group L Protein 
Descriptor Spanish:   Proteína del Grupo de Complementación L de la Anemia de Fanconi 
Descriptor Portuguese:   Proteína do Grupo de Complementação L da Anemia de Fanconi 
Tree Number:   D08.811.464.938.750.186
D12.776.313.937
Definition English:   An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN. 
History Note English:   2006(2003) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50585 
Unique Identifier:   D052240 

Occurrence in VHL:
 

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