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CYCLIN-DEPENDENT KINASE INHIBITOR P18
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase Inhibitor p18
Descriptor
Spanish
:
Inhibidor p18 de las Quinasas Dependientes de la Ciclina
Descriptor
Portuguese
:
Inibidor de Quinase Dependente de Ciclina p18
Tree Number:
D12.644.360.225.300
D12.776.167.187.300
D12.776.476.225.300
D12.776.624.776.355.300
Definition
English
:
An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL
growth
, organ enlargement, and a variety of
NEOPLASMS.
Pharmacological Action:
Protein Kinase Inhibitors
History Note
English
:
2006(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50929
Unique Identifier:
D050763
Occurrence in VHL
:
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