Search on: ANKYRINS 
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Descriptor English:   Ankyrins 
Descriptor Spanish:   Ancirinas 
Descriptor Portuguese:   Anquirinas 
Tree Number:   D12.776.124.080
D12.776.543.080
Definition English:   A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist. 
Indexing Annotation English:   membrane proteins; from the Greek word for anchor with ref to their role in attachment of the cytoskeleton; /drug eff /ultrastruct permitted
History Note English:   93; was ANKYRIN (NM) 1979-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   30845 
Unique Identifier:   D017487 

Occurrence in VHL:
 

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